Hi everyone! Some of you may know me already. I'm Adventurer from the TTC boards. I started my journey a little over a year ago when I had just turned 39. I had never been pregnant (but also never tried). Since I met my DF later in life, we decided to go straight to a fertility clinic to get (me) checked out due to my age. It's a good thing I did because my first AMH done to assess ovarian reserve put me in the low fertility category (not that I was that surprised given my age). It was 12.7 pmol/L (in Canadian units) and 1.8 pg/ml (in American units). I had a total of 7 antral follicles, 4 on my right ovary and 3 on my left ovary. My initial FSH was 8.3 so in normal range. My day 3 LH and other tests were within normal except for my TSH which was a bit high at 5.43 so my RE put me on a very low dose of thyroid supplementation which corrected me to between 1.0-2.0. DF's SA was normal with 5% normal morphology (greater than 4% is considered fine). In the interests of time and maximizing chances, we decided to proceed straight to IVF.
Since my SHG revealed a polyp, I underwent a hysterscopic polypectomy. My RE insisted we wait 2 months before doing IVF so we did an IUI with few expectations since this is not the way to manage a 39 year old with slightly diminished ovarian reserve! But we thought, what the heck - you never know. Well, it turned out as expected - BFN. So on to IVF.
IVF Cycle #1 for a freeze all was in February of this year and the results were ok. FSH had climbed to 11.1 which is borderline high meaning I was edging towards premenopause faster than initially believed. On an antagonist protocol with 225 units Gonal F and 75 units Menopur, we got 7 eggs retrieved, 5 fertilized by ICSI and 4 blasts which were biopsied for PGS and were a disaster because we only got results on one out of 4! The one was abnormal. What a waste of $$ but I will not discuss this part further.
IVF Cycle #2 was in April and by this time I had been on vitamins and supplements including DHEA, ubiquinol, vit B6, vit D, vit E and royal jelly for at least a month. Plus, in mid March I began doing weekly acupuncture for the first time and starting drinking Chinese medicinal tea. I swear the acupuncture made a difference because my antral follicle count for April cycle was 16 (8 on right and 8 on left)!!! I couldn't believe it. Again on antagonist protocol (this time I insisted on starting Cetrotide on same day as stims even knowing it may slow growth) using 300 units Gonal F and 37.5 units Menopur, we got 19 eggs, 16 mature, 13 fertilized and 5 blasts for freezing. No transfer. We did not opt for the PGS this time.
IVF cycle #3 was in June and AFC count was 12 (6 on both sides). I had asked for my AMH to be repeated fearing that 2 IVF cycles would have depleted my egg supply but to my astonishment it came back in the normal range, almost double my initial AMH: 23.4 pmol/L or 3.3 ng/ml!! I almost entirely credit this to acupuncture but that's just my feeling. I'm sure the vitamins and supplements helped too, particularly vit. D. On the same protocol as in April, we got 16 eggs, 14 mature, 10 fertilized and 4 blasts frozen. No transfer again. They triggered me a day too late and I lost at least 2 of my leader follies (those eggs degenerated).