METFORMIN

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METFORMIN

Postby jessicabuff » Tue May 03, 2011 3:20 pm

How is it supposed to help you get pregnant?
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Postby georgiagirl1214 » Tue May 03, 2011 3:44 pm

I have never took it but I have read that it helps women with PCOS to O....hope this helps...sorry it wasnt much but I didnt wanna read you question and not respond....helps you to lose weight to I heard! GL!!!
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Postby georgiagirl1214 » Tue May 03, 2011 3:46 pm

Metformin and Pregnancy

Use of Metformin (FDA pregnancy Category B) has not been linked to birth defects in animals or humans. Metformin has been used off-label to achieve pregnancy and throughout the first trimester in order to reduce the risk of spontaneous abortion. Insulin sensitized medications have no risk of causing multiple pregnancies. Although Metformin is not approved for use during pregnancy, it is being used more commonly off-label through the first trimester since it has been postulated, but not proven by randomized prospective trials, that its use may reduce the risk of early pregnancy miscarriages and reduce the risk of gestational diabetes with its sequela.

Metformin and Ovulation Induction with Gonadotropins and IVF

Metformin also improves clomiphene resistant anovulation in women treated with follicle-stimulating hormone. Use of metformin significantly reduced the rate of cycle cancellation and ovarian hyperstimulation syndrome in comparison to gonadotropins alone. Research has shown PCOS patients undergoing IVF develop a greater number of poor quality oocytes demonstrated by lower fertilization and pregnancy rates probably due to higher levels of intrafollicular androgens. In one prospective study, patients undergoing IVF treated with FSH and metformin had a significant increase in the number of mature oocytes retrieved, fertilization rates, and number of embryos produced.
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Postby bean629 » Tue May 03, 2011 7:28 pm

I do not have pcos but I did have very irregular cycles (anywhere from 40 to 75+ days). My doctor tried me on metformin and within 6 months my cycle has regulated itself to about 32 days which is really awesome for me.

Metformin helps your body use insulin correctly and is a medicine prescribed to diabetics. There is a link though between fertility/pregnancy and your body's ability to use insulin correctly. Metformin helps the body use insulin correctly and so in some women it helps them ovulate, makes them more fertile due to this and it has even shown to help prevent miscarriages and prevent gestational diabetes.

That being said often times doctors have to give very high doses (1500 mg/day) and it can cause nausea and abdominal troubles. I only take 500 mg and have no troubles with either but I also take it right before bed.

For me personally it has been wonderful - I am ovulating regularly!!! Not pregnant yet but have only been actively trying 2 months.
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