IUI, 5 >18mm follicles, ovidrel trigger...BFP??

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IUI, 5 >18mm follicles, ovidrel trigger...BFP??

Postby mcbmamarn » Wed May 25, 2016 10:05 pm

Hi Ladies!!

I am new here. :) Hubby and I have unexplained infertility. We just did out first IUI the 17th, using gonal-f, and ovidrel. I was on a pretty low does of goal-f, but responded robustly to treatment. I had 9 BIG follicles ready to go on the day of IUI, so my doc did a reduction. That was HANDS DOWN the most painful experience of my life, and I have had three cesareans. They removed all but 5 follicles, did the first IUI and then I returned the next day for the second IUI. My doc told me we had a high chance of conceiving as hubs count was awesome, and our issue was not a fertilization issue. She also said I would become pregnant in 5 days as the sperm meets the egg 24 hours earlier than with intercourse.

So today is 9 days past trigger/8 dpIUI. I have been getting positive urine HPT's, and am wondering if this is really a bfp. I am a nurse as well, and had my coworker draw my blood a couple time and test the serum on one of those urine/blood combo cassette tests. From my research, the 250 mcg Ovidrel is = to 6,500 iu of HCG. According to the insert in the Ovidrel box, half life is 29.2 hours, with an excretion rate of 0.51 L/hr. I found this handy calculator that broke the excretion rate down:

DOSE: 0.25 mg Ovidrel

29 hours: 50% dose=3250 iu
58 hours: 25% dose=1625 iu
88 hours: 13% dose=845 iu
117 hours: 6% dose=390 iu
146 hours: 3% dose=195 iu
175 hours: 1% dose=65 iu
204 hours (8.5 days): 0% dose=0 iu

Attached is a pic of my tests. The left is urine and the right is blood. The top was yesterday (7dpo) and the bottom was today (8dpo).

Let me know what you ladies think.

Baby dust!!!!
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Joined: Wed May 25, 2016 9:24 pm

Re: IUI, 5 >18mm follicles, ovidrel trigger...BFP??

Postby stayinghopeful31 » Tue May 31, 2016 10:38 am

Hi Mcbmamarn- when you say the doc did a reduction, what does that mean exactly?! Any updated- did you end up with a BFP? I have heard that it can take up to 14 days for the trigger shot to leave your system and I know that there are ladies that test it out of their system. If you didn't test out the trigger there really won't be any way of knowing until you are a little further along in the cycle. Do you have a beta scheduled for 14DPIUI? I mean with 5 mature follicles and your DH's count being good I would say you probably have a pretty good shot of getting a BFP. Good luck- can't wait to hear an update!
Me:32 DH:32 Off BCP since February 2014 TTC #1 since July 2014

3/17-1st RE appt. Deemed "Unexplained IF"
March 2016- 1st Clomid cycle (50mg) CD3-7. U/S 3/31- 4 follicles- Right side 3@12, left side-1 @24 1st IUI CD14 (4/2) BFN
April 2016-2nd Clomid cycle (50mg) CD3-7. U/S- 4/29- 21.5 Rt/25 left. Ovidrel Trigger. 2nd IUI (CD13) 4/30. BFN
May 2016- 3rd Clomid cycle (50mg) CD5-9. U/S 5/23- 18,17,11. U/S 5/25- Rt- 21,17,12-Triggered. 5/26 IUI #3. BFN
June 2016- 4th Clomid cycle (50mg) Cyst on left ovary (completely gone by CD12 U/S) IUI #4 BFN
July 2016- Natural cycle while prepping for IVF with ICSI for August's cycle
August 2016- IVF cycle cancelled. Lab shuts down at the end of August.
Sept 2016- IVF cycle- start stims 9/6, ER 9/16. BFP 9/30 EDD 6/7/17

Posts: 795
Joined: Mon Sep 28, 2015 7:29 am

Re: IUI, 5 >18mm follicles, ovidrel trigger...BFP??

Postby Danaa » Tue May 31, 2016 1:01 pm

I had 3 trigger shots and I can say that an Ovidrele shot can last up to 13days in ur body.good luck to you.
My Ovulation Chart
Me 29
DH 31
After 3 years in which we tried everything we are doing IVF in Greece with Iakentro Athens.
Short Protocol with Bemfola and Cetrotide
19mature eggs and we have 9 day5 blasto.
FET#1 ended in a very early loss,chemical pregnancy.
FET#2 ended in a loss at 22w due to IC,my boys will be forever in my heart .
FET#3 MMC at the 10 weeks ultrasound.
FET#4 2018
Posts: 10056
Joined: Wed Nov 12, 2014 5:54 am

Re: IUI, 5 >18mm follicles, ovidrel trigger...BFP??

Postby MrsRoulette » Sat Jun 04, 2016 7:25 pm

Hey y'all! New to this forum. I am on day 2 of Gonal F and scheduled for US on Monday. Femara alone produces one follile for me and that is at 7.5 mg day 3-7. So this time we added Gonal F 75 iu and I feel like maybe it should have been higher. I do not feel ANY ovary discomfort at all, unlike other months. Crossing my fingers for more than 2 follicles so my IUI is not cancelled. I would be totally bummed.I would probably take too many follies news better than oh, there is nothing to measure.
IVF would be our next step if this cycle is a bust but I have enough Gonal F for another cycle just won't be able to afford IUI.
I do not know what the doc's cutoff is on the follies for him to do an IUI. But I will make him do an estradiol level check if i have more than he likes because then he can say how many are mature.
All the best guys!
Been TTC Since Dec 2011
Hubby's SA: motile density. 10% (60% or greater is good) My Cycles: 32 days. 29 with femara
1st round of Clomid June 2013 (cd5-9). On cd 21, prog level 26.1 BFN
2nd round of Clomid July 2013 (cd5-9). On cd 21, prog level 29.1 BFN
April 14, 2016 IUI - BFN (Femara 5 mg day 3-7), Ovidrel Trigger) 1 follie.
May 1-6, 216 Femara 7.5 mg (day 3-7). One small follicle. Cancelled cycle
May 30th, 2016 - Femara 7.5 mg (day 3-7). + Gonal F Injections 150 iu (day 7-12)- 22.5,16.7, 9 mm follies
Ovidrel day 12, IUI day 13 06/09/2016 BFN
FertileCM, Fertility Blend, herbal fertility tea from Kenya - BFP!!!!!!
We prayed, hoped, waited for our little miracle. Now God has started in me the miracle of creation. So blessed!!
Posts: 142
Joined: Wed Jun 12, 2013 7:13 am

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