Metformin and Provera, no Clomid

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Metformin and Provera, no Clomid

Postby driasue » Sat Jul 21, 2012 1:20 am

I have been ttc about two years. Have had PCOS for 15 years. Been having 2-4 week periods for last 3 years with 1-3 weeks a month no bleeding. Been taking Met since early Feb. My dr has not wanted to give me Clomid even though I asked repeatedly. She told me to take Met & lose weight first. I grudgingly took off 10 lbs. After ultrasound, she consulted with an obgyn who said it would be "dangerous" for me to take Clomid. Instead they put me on provera for 10 days. Said after af from provera, to wait 30 days, take a pregnancy test, and if bfn, do another 10 days provera. btw af on provera was shorter (7 days), but way crazy heavy (had to wear depends! lol). Has anyone heard of success with no clomid, just Met & provera?
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Postby reapette » Tue Jul 24, 2012 5:38 pm

didn't want to read and run. Have you consulted another doctor for a second opinion? I have been on both metformin and provera before but never had a repeated treatment. I took metformin 100mg for 6 months and only took provera if my cycles went over 60 days. so i'm not honestly sure what your doctors plan is but i'd see someone else who will repect your wishes.
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Postby driasue » Thu Aug 02, 2012 6:30 pm

Thanks for the reply! I've got an appt & I'm going to insist on clomid. If not, I'm just going to try Met and lose weight. I have not found a dr. that will get over my weight and and actually try to help.
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Postby HawkeyeGirl16 » Sun Aug 05, 2012 8:02 am

First line treatment for PCOS is weight loss and metformin if you are significantly overweight. Even a 5-10% weight loss can restore fertility. Plus, metformin sometimes takes a few months before it starts helping. The reason that clomid or other stims could be dangerous for some women with PCOS is because we typically have a ton of follicles sitting around and several of them could respond at the same time and cause hyperstimulation.

That being said, it would be very rare to have that problem with clomid, although you may be at an increased risk of having twins or triplets. My RE was very slow to increase any of my medications while I was TTC with PCOS. I ended up being very resistant to medications and didn't respond to clomid or femara. After starting injectables, I still wasnt having much luck. Then, I had a huge response to the same doses of medications that I had been taking in the past and ended up pregnant with triplets. Unfortunately, I lost them to incompetent cervix. Because of this unpredictable response and the risks of a high order multiple pregnancy, some REs are very cautious with PCOS.
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Postby MrsDimples » Mon Aug 27, 2012 12:31 pm

I ABSOLUTELY think you need to find another Dr!!! Is this a specialist? Or just an ob/gyn? My ob/gyn was not going to help me at all until I got down to a certain # on the scale....uhh.....ok. I sat with that for a year. Became very depressed. Finally was snapped out of it, made an appt with an infertility specialist and I'm about to start clomid. I didn't even have to ask. It's what he wanted to do.
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Round 3 Clomid- 150 mg 11/2012- Trigger shot 11/30/2012...BFN
Round 4......150mg clomid (4 days only) Trigger 12/30.
BFP 1/11/2013!!!!!
Due 9/24/2013!!!!!

Beta #1 (9dpo)- 10
Beta #2 (12dpo)- 54
Beta #3 (21dpo)- 2,017!

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Postby driasue » Fri Aug 31, 2012 10:38 pm

Wow, that sounds a lot like me. I've talked to several Drs and they seem to say the same. I finally begged her to put me on clomid, and she agreed. She admitted that there were no extra health risks. I have also stepped up the weight loss, so we'll see. I start clomid on Sunday. Trying not to get my hopes up too much, but excited!
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Re: Metformin and Provera, no Clomid

Postby driasue » Sat Oct 06, 2012 10:14 pm

Just an update here. The provera has done nothing to help and has taken away my natural af. For the past two cycles, af has not come naturally. I have waited til 2 weeks late with no bfp, then caved and taken the provera. After 3 years of regular (if not normal) periods before, after provera, nothing. Btw no af + no bfp is worse than af showing up in my opinion. At least there is a "for sure" that way rather than a bunch of guessing.
Me 32
DH 36
PCOS since 1998
TTC #1 since September 2010
Never O'd as far as I know since PCOS
Clomid round #4 100mg

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