I've been ttc for almost 2 years and have been thru three failed IVF cycles. (2 fresh and 1 frozen). Recently, after switching clinics, my new RE has discovered that I am lacking beta-3 integrin...the "sticky stuff" in the uterine lining that allows an embie to implant. I am currently on a 2 month depo-lupron treatment and plan on doing another FET at the end of September. It's been a l o n g road but will definetely be worth it when the "special one" arrives one day!!