Progesterone support after IVF/FET

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Progesterone support after IVF/FET

Postby queenypink » Thu Apr 20, 2017 8:26 pm

Hello ladies!

I'm wondering what your protocol is after your transfer (fresh or frozen) in terms of progesterone support.

My clinic has a new protocol apparently -- I will be taking Estrace twice a day, two Prometrium caps three times a day vaginally, and PIO injections every third day, and will stay with this regimen until 10 weeks if the transfer is successful (a thousand fingers crossed!!!)

My last fresh cycle was super easy - 2x prometrium 2x daily -- super simple.

I picked up my PIO from the pharmacy today. What makes me nervous is the little leaflet that explains precautions, risks, etc, talks about how it should not be taken during pregnancy, especially for the first four months.

Wtf! Haha this makes me so nervous, but at the same time I think PIO injections are common after transfer. Maybe the leaflet is assuming I'm not using these for fertility reasons and assumes my natural progesterone levels are perfectly wonderful...

Me: 33 Yrs. Cervical cancer SURVIVOR! Treated w/radical trachelectomy, lymphadenectomy & circlage. Sucky FSH (12) & AMH w/in the normal/low range
DH: 38 Yrs. SA came back low-ish
Official Dx: Unexplained

Five unmedicated IUI's - All Neg.
| 29.03.14 | 29.04.14 | 23.06.14 | 22.07.14 | 19.08.14 |

IVF #1: Baseline Mar 17/15
ER Mar 30th -- 15 eggies collected, 13 mature, 10 fertilized naturally
ET Apr 4th -- 4AA Blastocyst Embaby <3
6 perfect frosty day 6 blasts/expanded blasts

BFP at 8dp5dt
Beta 10dp5dt April 14th - 179
Beta #2 12dp5dt Apr 16th - 519
Beta #3 16dp5dt Apr 20th - 2698
Beta #4 20dp5dt Apr 24th - 8337
DD born Oct '15 at 32wks gest. She's perfect!

FET #1: May 2/17 BFN
FET #2: June 6/17

BFP 8dp5dt
Beta 10dp5dt - 498
Beta 12dp5dt - 1473
Beta 19dp5dt - 11 430
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Re: Progesterone support after IVF/FET

Postby KeepTrying15 » Fri Apr 21, 2017 5:19 am

Hi there! For my first IVF, I did estrogen injections from day 1 then added PIO injections (1cc 2x day) starting 3 days before the transfer up until my negative beta. It's very common to use PIO so I wouldn't worry too much about it. It was similar to an FET since my eggs were frozen then thawed/fertilized. Interestingly, I'm starting the process for another one with a new doctor and will be using frozen eggs again, this doctor is suggesting a natural cycle, which they will allow my body to naturally produce estrogen and to ovulate then if my progesterone is enough we won't do any support, otherwise they'll put me on suppositories and/or PIO. I haven't decided yet if I'll do the natural cycle, not sure if I trust my body to do what it's supposed to do lol.

Good luck to you!!!
3 early losses (natural bfps)
IUI #1-3 - BFN
IVF #1 - transferred 2 3-day embryos - BFN
IVF #2 - converted to IUI - BFP! - MC at 5 weeks
IVF #3 - 1 hatching 5 day blast transferred - 4 frosties
5dp5dt bfp :D
Beta #1 10dp5dt = 264
Beta #2 12dp5dt = 699
6w5d - HR 129 Image
8w2d - HR 174 Image

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Re: Progesterone support after IVF/FET

Postby @whenmytruerainbow » Thu Apr 19, 2018 3:29 am

Hi! I did, but frankly, forgot once. I never felt like it was that critical. Sorry if this is TMI in advance. Put it in while you are laying in bed. After you squeeze the thing don't release the pressure while it is still in you. Because I think it's when it sucks the stuff back..
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